[Ortho] ScienceDirect Alert: Bone, Vol. 46, Supp. 1, 2010

Сб Мар 20 08:56:35 YEKT 2010

New Volume/Issue is now available on ScienceDirect!

*  Bone
   Volume 46, Supplement 1, Pages S1-S90 (March 2010)
   Safety Assessment - Safety Assessment
   Edited by Luis Gilbert Valerio, Jr.
   http://www.sciencedirect.com/science/issue/4987-2010-999539999.8998-1783720

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TABLE OF CONTENTS

1) Editorial Board
Pages i-ii
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2) IBMS DAVOS 2010: Committee Information
Pages S1-S2
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3) 2010 IBMS Davos Workshop: Bone Biology & TherapeuticsDraft Program
Pages S3-S8
Dummy Author
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4) Chondrogenesis and Pattering
Page S9
Stefan Mundlos
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5) Hedgehog signaling in cartilage pathology: a role in osteoarthritis and chondrosarcoma
Page S9
Benjamin Alman
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6) Real time imaging of Gene Expression
Page S10
Vasilis Ntziachristos, Vasilis Ntziachristos
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7) Cell Cycle-Arrested Osteoclast Precursors
Page S10
Naoyuki Takahashi
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8) Chemokine and lipid mediator-mediated control of osteoclast migration visualized by in vivo bone imaging: A novel point of regulation for bone homeostasis
Pages S10-S11
Masaru Ishii
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9) Impact of sympathetic neuron signals on bone remodeling and cancer metastasis
Page S11
Florent Elefteriou
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10) Osteocyte Remodeling of their Perilacunar/canalicular Matrix: Hormonal/Mechanical Regulation
Page S11
Lynda Bonewald
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11) Sclerostin regulation and mode of action
Page S11
Michaela Kneissel
http://www.sciencedirect.com/science?_ob=GatewayURL&_method=citationSearch&_urlVersion=4&_origin=SDVIALERTASCII&_version=1&_uoikey=B6T4Y-4YM4WM5-C&md5=045f097c105a9d13164c4102ec4f7952

12) Mechanisms of Bone Deformation and Fracture
Page S12
Himadri Gupta, Peter Fratzl, Michael Kerschnitzki, Stefanie Krauss, Jong Seto, Wolfgang Wagermaier, Gunthard Benecke, Peter Boesecke, Sergio Funari, John Currey, Jose Estevez
http://www.sciencedirect.com/science?_ob=GatewayURL&_method=citationSearch&_urlVersion=4&_origin=SDVIALERTASCII&_version=1&_uoikey=B6T4Y-4YM4WM5-D&md5=49b6191afe50a71445ca0beb923dd09e

13) Genomewide Studies in Osteoporosis
Page S12
Matt Brown
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14) T Cells Involvement in PTH Anabolic Actions
Page S12
Roberto Pacifici
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15) β-catenin is a key mediator in the development of intervertebral disc tissue degeneration
Pages S12-S13
Di Chen
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16) Therapeutic Targeting to Bone: Enzyme Replacement Treatment for Hypophosphatasia
Page S13
Michael Whyte
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17) Noninvasive Assessment of Structural and Mechanical Properties of Trabecular and Cortical Bone by Proton, Deuteron and Phosphorus Magnetic Resonance
Pages S13-S14
Felix W. Wehrli
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18) Initiators and Inhibitors in Vascular Calcification
Page S14
Catherine Shanahan
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19) Lessons Learned from CIC-7 Deficiency: Are All Anti-Resorptives the Same?
Page S14
Morten Karsdal
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20) Cathepsin K - A Novel Molecular Target for Treatment of Osteoporosis: Discovery of Odanacatib
Pages S14-S15
Sevgi Rodan
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21) The Pathophysiology and Treatment of Glucocorticoid Induced Osteoporosis
Page S15
Nancy Lane
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22) Sclerostin is an Important Target for Stimulating Bone Formation, Restoring Bone Mass and Enhancing Fracture Healing
Page S15
David Ke, Desmond Padhi, Chris Paszty
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23) Calcium supplement effects on vascular events - is it worth the risk?
Pages S15-S16
Ian Reid
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24) Nanotherapeutics: Novel engineered nanoparticles promote bone accretion in vivo
Page S16
George Beck, Shin-Woo Ha, Corinne Camalier, Tatyana Vikulina, Masayoshi Yamaguchi, Li Yan, Jin-Kyu Lee, M. Neale Weitzmann
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25) The Adverse Effects and Safety of Bisphosphonates
Page S16
Steve Cummings
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26) Genetics of muscle
Pages S16-S17
Eric Orwoll
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27) Vitamin D is a multifunctional hormone
Page S17
Roger Bouillon
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28) How long to treat and what to do when you stop?
Page S17
Serge Ferrari
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29) Denosumab to Prevent Disease and Treatment-Related Skeletal Complications in Men with Prostate Cancer: Emerging Evidence
Pages S17-S18
Matthew Smith
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30) Anti-tumor effects of bisphosphonates in man - myth or reality?
Page S18
Robert Coleman
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31) The role of disseminated tumour cells and circulating tumour cells in the early development of (bone) metastasis
Page S18
Klaus Pantel
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32) Growth Hormone in Combination with Bisphosphonate Treatment in Osteogenesis Imperfecta
Pages S18-S19
Francesco Doro, Paolo Cavarzere, Elena Monti, Giacomo Venturi, Silvano Adami, Franco Antoniazzi
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33) GnRH analogue treatment and decrease of bone mass density (BMD) in a patient with Osteogenesis Imperfecta (OI) and Central Precocious Puberty (CPP)
Page S19
Francesco Doro, Elena Monti, Paolo Cavarzere, Silvia Perlini, Evelina Maines, Franco Antoniazzi
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34) BONE DENSITY DECREASED IN FEMALE CHILD
Page S19
Antonio Bazarra-Fernandez
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35) HORMONE REPLACEMENT THERAPY AND CALCITONIN IN WOMEN WITH BONE MASS LOSS
Page S20
Antonio Bazarra-Fernandez
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36) RISEDRONIC ACID AND RALOXIFENE IN POST-MENOPAUSAL WOMEN WITH OSTEOPOROSIS
Page S20
Antonio Bazarra-Fernandez
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37) COMBINED USE OF CALCITONIN AND ALENDRONATE IN HIV-INFECTED WITH BONE MASS LOSS
Page S20
Antonio Bazarra-Fernandez
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38) TREATMENT OF CONGENITAL PSEUDARTHROSIS OF THE TIBIA USING RECOMBINANT BONE MORPHOGENETIC PROTEIN AND BISPHOSPHONATES
Pages S20-S21
Oliver Birke, Aaron Schindeler, Manoj Ramachandran, Lauren Peacock, Kathy Mikulec, Alyson Morse, Nicole Yu, Paul Baldock, Chris Cowell, Craig Munns, Michael Bellemore, David Little
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39) Safety and Tolerability of Bazedoxifene in Postmenopausal Women With Osteoporosis: Results of a 5-year, Randomized, Placebo-controlled Phase 3 Trial
Page S21
T. de Villiers, D. Kendler, A. Chines, P. Lips, J. Kaufman, A. Levine, N. Mairon, C. Codreanu, D. Felsenberg, J. Brown
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40) The prevention of bone mineral density loss in glucocorticoid-treated inflammatory bowel disease patients
Pages S21-S22
Miro Cokolic, Mitja Krajnc
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41) The Ability of Bisphosphonates and Their Analogues to Penetrate the Osteocyte Network is Dependent on Affinity for Bone
Page S22
Fraser Coxon, Anke Roelofs, Alan Boyde, Mark Lundy, Charles McKenna, Katarzyna Blazewska, Shuting Sun, Boris Kashemirov, Xuchen Duan, Graham Russell, Aysha Khalid, Michael Rogers, Frank Ebetino
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42) Abnormal Bone Microindentation Test in a Diaphiseal Femur Fractur After Long-Term Bisphosponates
Page S22
Roberto Güerri, Adolfo Diez-Perez, Gemma Vila, Elisabet Lerma, Ignasi Rodriguez-Pinto, Leonardo Mellibovsky, Enric Caceres, Xavier Nogues, Paul Hansma
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43) Determination of the relative bone mineral-binding affinities of bisphosphonates by using hydroxyapatite-column chromatography combined with mass spectrometric analysis
Page S23
Xuchen Duan, Zhidao Xia, Hao Zhang, Mike Quijano, Roy Dobson, Bobby Barnett, James Triffitt, James Dunford, Frank Ebetino, R. Graham Russell
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44) Designed mutants of human farnesyl pyrophosphate synthase (FPPS) help to characterise the interactions of nitrogen-containing bisphosphonates with Tyrosine 204 and Phenylalanine 239 side-chain residues
Page S23
Maria Tsoumpra, Bobby Barnett, Aaron Kwaasi, Rick Walters, Frank Ebetino, R. Graham Russell, Udo Oppermann, James Dunford
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45) Re-initiation of risedronate 5 mg daily therapy in patients on long-term treatment after 1 year of discontinuation: effects at 9 and 10 years
Pages S23-S24
Richard Eastell, Rosemary Hannon, Dietrich Wenderoth
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46) Significantly Reduced Burst Release by Sequestration of Protein Delivery Vehicle Within Unique Three-Phase Composite Scaffold for Bone Tissue Engineering and Regenerative Medicine
Page S24
David Grant, Mischa Müller, Philip Tominac, Limin Guan, Kyla Sask, John Brash, John Davies
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47) Complementary and Alternative Therapies : Rheumatoid Arthritis
Page S24
Vijaya Juturu
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48) Improvement of osteoporotic bone quality through minimally invasive laser therapy
Pages S24-S25
Chang-Yong Ko, Dongyeon Kang, Dong hyeon Seo, Yeonhang Ryu, Byungjo Jung, Han-Sung Kim
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49) SCLEROSTIN NEUTRALISING ANTIBODY ENHANCES HEALING OF TIBIAL METAPHYSEAL DEFECT IN AN OVX RAT MODEL
Page S25
Michelle McDonald, Alyson Morse, Lauren Peacock, Kathy Mikulec, Paul Baldock, Min Liu, Hua Zhu “David” Ke, David Little
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50) CHANGES OF BLOOD VESSELS OF VENTRAL PART OF SPINE IN THE CONDITIONS OF AT PROTRACTED RUN IN EXPERIMENT
Pages S25-S26
Vladimir Koveshnikov, Andrey Sak
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51) BONE MINERAL ULTRASTRUCTURE IN WHITE ADULT RATS UNDER THE IMPACT OF THE DIFFERENT MODES OF CHRONIC HYPERTHERMIA IN COMBINATION WITH THE PHYSICAL ACTIVITY AND POSSIBLE CORRECTION WITH INOSINE
Page S26
Svetlana Smolenchuk, Vladyslav Luzin
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52) Bazedoxifene reduces non-vertebral fractures in patients at high probability of fracture
Page S26
Eugene McCloskey, Helena Johansson, Arkadi Chines, Anders Oden, John Kanis
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53) SCLEROSTIN NEUTRALIZING ANTIBODY ENHANCES BONE HEALING DURING DISTRACTION OSTEOGENESIS IN RATS
Page S27
Michelle McDonald, Lauren Peacock, Kathy Mikulec, Oliver Birke, Min Liu, Scott Wasserman, Hua Zhu “David” Ke, David Little
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54) Differential effects of angiotensin II-receptor blockade on vascular and skeletal manifestations of Marfan syndrome
Page S27
Harikiran Nistala, Aaron Rifkin, Sui Lee Arteaga, Maria del Solar, Luca Carta, Francesco Ramirez
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55) Effect of Denosumab on the Incidence of Hip and New Vertebral Fractures in Postmenopausal Women With High Fracture Risk: A Subanalysis of the FREEDOM Study
Pages S27-S28
Kurt Lippuner, Jonathan Adachi, Steven Cummings, Zulema Man, Jordi Farrerons, Ove Törring, John Gallagher, Mike McClung, Nathalie Franchimont, Javier San Martin, Andrea Wang, Steven Boonen
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56) The Effect of Denosumab on Bone Turnover Markers (BTM) in Postmenopausal Women With Osteoporosis
Page S28
Steven Cummings, Andrea Wang, Javier San Martin, Mike McClung, Christiansen Claus, Cesar Libanati, Ethel Siris, Richard Eastell
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57) Denosumab and Alendronate Have Different Effects at the Ultradistal Radius in Postmenopausal Women With Low Bone Mass
Pages S28-S29
Cesar Libanati, Ego Seeman, Thierry Thomas, Steven Boyd, Stephanie Boutroy, Elizabeth Shane, David Hanley, Cesar Bogado, Angela Cheung, Sharmila Majumdar, Deborah Sellmayer, Ann Kearns, Pierre Delmas, Michelle Fan, Jose Zanchetta
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58) Preservation of Cancellous Bone Microarchitecture by an Antagonist of IL-15 in a Mouse Model of Colitis
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Dominique Pierroz, Serge Ferrari, Sylvie Ferrari-Lacraz
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59) INFLUENCE OF ZOLENDRONIC ACID INFUSION ON STATE OF CARDIOVASCULAR SYSTEM IN POSTMENOPAUSAL WOMEN
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Vladyslav Povoroznyuk, Nataliia Grygorieva, Volodymyr Vayda, Nataliya Balatska, Nataliia Dzerovych
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60) INTERMITTENT PAMIDRONATE THERAPY TO TREATMENT CORTICOSTEROID-INDUCED OSTEOPOROSIS
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Vladyslav Povoroznyuk, Tetyana Orlyk, Tetyana Karasevskaya
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61) INTERMITTENT PAMIDRONATE THERAPY FOR TREATMENT OF SEVERE OSTEOPOROSIS IN POSTMENOPAUSAL WOMEN
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Vladyslav Povoroznyuk, Tetyana Orlyk, Volodymyr Vayda, Maryna Bystrytska, Nataliia Dzerovych
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62) EFFECT OF ZOLENDRONIC ACID IN TREATMENT OF POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS
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Vladyslav Povoroznyuk, Nataliia Grygorieva, Volodymyr Vayda, Nataliia Dzerovych, Nataliya Balatska
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63) Whole bone testing in small animals: Why do our results not reach statistical significance? Impact and reduction of systematic failure
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Peter Prodinger, Dominik Bürklein, Eduardo Grande–Garcia, Daniela Angerbauer, Jonathan Herberholz, Thomas Tischer
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64) Esophageal ulceration in a patient with kyphoscoliosis and newly diagnosed osteoporosis
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Peter Rainer, Andreas Eherer, Cord Langner, Winfried Graninger, Kurt Weber
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65) Odanacatib in the Treatment of Postmenopausal Women with Low Bone Mineral Density: 3-Year Continued Therapy and Resolution of Effect
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Ian Reid, John Eisman, Henry Bone, David Hosking, Michael McClung, Rene Rizzoli, Heinrich Resch, Nadia Verbruggen, Carolyn Hustad, Carolyn DaSilva, Arthur Santora, Avery Ince, Antonio Lombardi
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66) Sustained Efficacy of Bazedoxifene in Preventing Fractures in Postmenopausal Women With Osteoporosis: Results of a 5-year, Randomized, Placebo-controlled Study
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S. Silverman, A. Chines, J. Zanchetta, H. Genant, D. Kendler, F. Rio de la Loza, A. Kung, G. Constantine, J. Adachi
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67) A Soluble BMP Antagonist Polypeptide Increases Bone Mass and Improves Bone Strength
Pages S32-S33
Nicolas Solban, Milton Cornwall-Brady, Yoshimi Kawamoto, Dianne Sako, June Liu, Kathleen Tomkinson, Benjamin Umiker, Travis Monnell, Shana Walrond, Rita Steeves, Kathryn Underwood, Ravi Kumar, Jasbir Seehra, R. Scott Pearsall
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68) Treatment-Naive Osteoporosis Patients Strongly Prefer Once-Yearly Intravenous Therapy: A Time Trade-Off Study
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John Wark, Elizabeth Hristov, Richard Osborne, Andrew Dalton
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69) Treatment with acetaminophen/paracetamol or ibuprofen alleviates post-dose symptoms related to intravenous infusion with zoledronic acid 5 mg
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John Wark, Christopher Recknor, Olga Ryabitseva, Jospeh Chiodo III, Peter Mesenbrink, Tobie De Villiers
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70) Is zoledronate toxic to human periodontal and dental pulp fibroblasts?
Pages S33-S34
Hermann Agis, Janina Blei, Barbara Cvikl, Georg Watzek, Reinhard Gruber
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71) OSTEOPOROSIS AND STDs WITH MENAUPAUSE
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Antonio Bazarra-Fernandez
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72) The Corning Osteo Assay Surface for the Study of Bone Metastatic Cancer
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Hanna Rao, Jian Tan, Janie Causer, Chris Wolcott, Megan Wang, Jessica Brown, Jaishree Trikha, Edward Fewkes, Fawad Faruqi, James Beltzer
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73) COMPARE - Results of a randomised study to assess the renal safety and efficacy of ibandronate and zoledronate in multiple myeloma patients
Pages S34-S35
Raoul Bergner, Hartmut Goldschmidt, Martin Kropff, Wolfram Pönisch, Claudia Kiewitz, Wolfgang Knauf
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74) Renal safety of ibandronate in the treatment of myeloma patients
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Raoul Bergner, Breuer Jochen, Michael Uppenkamp, Andreas Sandermann, Martin Hoffmann
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75) Doxorubicin Therapy Causes Additional Bone Loss in Preclinical Osteolytic Breast Cancer Model
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Swati Biswas, Austin Ayers, Anwesa Chakrabarti, Steve Munoz, Joshua Johnson, Gregory Mundy
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76) Oncostatin M leads to opposite effects on the proliferation of different primary bone tumors
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Emmanuelle David, Bénédicte Brounais, Dominique Heymann, Francoise Rédini, Frederic Blanchard
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77) Effect of ibandronate infusion duration (15 min versus 60 min) on renal function in breast cancer patients with bone metastases
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Luc Frimat, Alain Lortholary, Sophie Abadie-Lacourtoisie, Fawzia Mefti-Lacheraf, Eric Pujade-Lorraine, Claudia Lefeuvre, Pascal Bleuzen, Philippe Morvan, Carole Dür, Xavier Pivot
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78) Results of a prospective, randomized, double-blind, double-dummy, Phase 3 study comparing denosumab with zoledronic acid for the treatment of breast cancer patients with bone metastases
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Jean-Jacques Body, Alison Stopeck, Yasuhiro Fujiwara, Allan Lipton, Guenther Steger, Maria Viniegra, Michelle Fan, Roger Dansey, Jun Susie, Braun Ada
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79) Modulation of FPPS's activity following NBPs therapy: clinical implications
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Sara Galluzzo, Michele Caraglia, Bruno Vincenzi, Silvia Angeletti, Chiara Spoto, Alice Zoccoli, Vladimir Virzi, Jacopo Fioroni, Monica Marra, Alberto Abruzzese, Giuseppe Tonini, Daniele Santini
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80) Involvement of the Slit2/Robo1 Pathway in Breast Cancer Bone Metastasis
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Vincent Gonin, Richard Bachelier, Blandine Deux, Sylvain Contié, Edith Bonnelye, Pamela Rabbitts, Jane Wu, Philippe Clézardin
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81) Long-term renal safety profile of ibandronate 6 mg infused over 15 minutes
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Roger Van Moos, Clemens Caspar, Rolf Steiner, Rahel Angst, Roman Inauen, Kerstin Schmieding, Beat Thürlimann
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82) Synergistic effect of Apomine and Lovastatin on osteosarcoma cell growth in vitro and in vivo
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Gatien Moriceau, Anke Roelofs, Regis Brion, F. Hal Ebetino, Mike J. Rogers, Dominique Heymann
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83) Effect of ibandronate on tumor cells in the bone marrow and in blood in patients with primary breast cancer. A pilot study
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Sabine Kasimir-Bauer, Cornelia Goldnau, Bahriye Aktas, Rainer Kimmig, Oliver Hoffmann
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84) Efficacy of loading-dose ibandronate for rapid pain relief in patients with advanced breast carcinoma and bone metastases
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Hans-Bernd Sittig
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85) Rapid reduction in bone pain following loading-dose ibandronate in patients with recently diagnosed bone metastases
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Andreas A. Kurth, C. Eberhardt, U. Stumpf, A. Müller
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86) Level of ibandronate in the kidney tissue after long-term application in rats with a normal and a limited renal function
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B. Siegrist, H. Faust, R. Bergner
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87) Bisphosphonate-associated osteonecrosis of the jaw bones: diagnosis and surgical management of a serious complication
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Sandra Umbreit, Christoph Reuter, Nils-Claudius Gellrich, André Eckhardt
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88) PHASE COMPOSITION OF THE BONE MINERAL AFTER IMPLANTATIONS INTO THE BONE DEFECT BIOLOGICAL HIDROXYAPATITE OK-015 WITH MANGANESE DOPANTS
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Vladyslav Luzin, Alexandr Lubenets, Dmitry Astrakhantsev
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89) Zoledronic acid induces IPP release from cancer cells which causes Vgamma9Vdelta2 T cell expansion in PBMCs
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Satu Arkko, Jukka Mönkkönen, Seppo Auriola, Irene Rosell Dronda, Ismahene Benzaid, Verena Stresing, Philippe Clezardin, Hannu Mönkkönen
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90) Do dose and acidic environment facilitate the manifestation of osteonecrosis of the jaw by increasing local bisphosphonate toxicity?
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Sven Otto, Christoph Pautke, Inga Drosse, Ines Westphal, Frieder Bauss, Michael Ehrenfeld, Matthias Schieker
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91) Expression of lyosophospholipase D/autotaxin by breast cancer cells controls bone metastasis formation by increasing osteoclast differentiation
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Marion David, Estelle Wannecq, Silvia Jansen, Blandine Deux, Johnny Ribeiro, Claire-Marie Serre, Sandra Grès, Nathalie Bendriss-Vermare, Mathieu Bollen, Jean-Sébastien Saulnier-Blache, Philippe Clézardin, Olivier Peyruchaud
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92) Zoledronic acid as new adjuvant therapeutic agent for Ewing's sarcoma
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Guillaume Odri, Sophie Dumoucel, Gaelle Picarda, Severine Battaglia, François Lamoureux, Nadege Corradini, Julie Rousseau, Franck Tirode, Karine Laud, Olivier Delattre, François Gouin, Dominique Heymann, Françoise Rédini
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93) Toxicity of Bisphosphonate-treated Bones to Epithelial Cells is Related to Bisphosphonate Potency - Mechanism of ONJ?
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Ian Reid, Usha Bava, Jillian Cornish
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94) RANKL silencing by siRNA improves therapeutic response of primary osteosarcoma to conventional chemotherapy
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Julie Rousseau, Virginie Escriou, Régis Brion, Séverine Battaglia, Dominique Heymann, Françoise Rédini, Valérie Trichet
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95) Frequent Intermittent Low-dose Therapy Accentuates the Antitumour Activity of the Bisphosphonate Risedronate In Vivo
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Verena Stresing, Blandine Deux, Ismahene Benzaid, Patrice Mathevet, Hal Ebetino, Philippe Clézardin
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96) Zoledronate-Induced IPP/ApppI (Phosphoantigen) Accumulation in Human Breast Cancer Cells Correlates with Vγ9VΔ2 T Cell-Mediated Cancer Cell Death In Vitro and In Vivo
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Ismahene Benzaid, Hannu Mönkkönen, Verena Stresing, Edith Bonnelye, Jonathan Green, Jukka Mönkkönen, Philippe Clézardin
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97) Ibandronate prevents deterioration of bone quality parameters after adjuvant chemotherapy with a taxane
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Ulla Stumpf, Marie Shea, Bettina Janz, Anja Mueller, Frieder Bauss, Peter Augat, Andreas Kurth
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98) Results From a Phase 3 Randomized, Double-Blind, Double-Dummy Clinical Trial Comparing Denosumab with Zoledronic Acid for the Management of Bone Metastases in Patients with Advanced Solid Tumors or Multiple Myeloma
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Roger von Moos, David Henry, Saroj Vadhan-Raj, Vania Hungria, Andrew Spencer, Vera Hirsh, Jianming Wang, Jun Susie, Yeh Howard, Roger Dansey
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99) Identifying epigenetic targets in osteosarcoma and differentiating osteoblasts
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Emma Baker, Carl Walkley, Natalie Sims, Louise Purton, T. John Martin
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100) Equilibrium binding affinity constants of the soy isoflavone genistein to all human full-length estrogen receptors present in human primary osteoblasts
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Igor Bendik, Christoph Riegger, Pascale Fuchs, Peter Weber
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101) MUSCLE CELL CONTRIBUTION TO INTRAMEMBRANOUS BONE HEALING IN A METAPHYSEAL DEFECT MODEL IN MICE
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Oliver Birke, Renjing Liu, Michelle McDonald, Alyson Morse, Nicole Yu, Aaron Schindeler, David Little
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102) QCT-based Finite Element Analysis Demonstrates Differential Effect of 12 months of treatment with Teriparatide on Vertebral Biomechanics in Postmenopausal Women Treated Previously with Risedronate or Alendronate
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Babul Borah, Yan Chevalier, Evelyn Quek, Gary Gross, John Stewart, Thomas Lang, Philippe Zysset
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103) Role of the Na-dependent phosphate transporters, PiT-1 and PiT-2, in the osteoblastic response to phosphate in vitro and in bone growth in vivo
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Annabelle Bourgine, Solmaz Khoshniat, Sara Diouani, Paul Pilet, Julie Lesoeur, Martial Masson, Lisa Oliver, Pierre Weiss, Laurent Beck, Jérôme Guicheux
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104) Osteoblastic Differentiation of Human Mesenchymal Stem Cells Benefits from Low Serum Level and BMP4 Supplementation
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Thomas Cordonnier, Alain Langonné, Pierre Layrolle, Luc Sensebé, Philippe Rosset, Jérôme Sohier, Frédéric Deschaseaux
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105) Molecular Mechanisms Involved in the Mitogenic Effect of Lactoferrin in Osteoblasts
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Jillian Cornish, Dorit Naot, Ian Reid
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106) In vitro assessment of osteoblast cell models for bone related research
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Ewa Czekanska, Jessica Hayes, Jim Ralphs, R. Geoff Richards
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107) Geometric Control of Tissue Growth
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Cécile Bidan, Krishna Kommareddy, Inderchand Manjubala, Monika Rumpler, Peter Fratzl, John Dunlop
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108) Forkhead Box O (FoxO) Transcription Factors in the Actions of 1,25-Dihydroxyvitamin D3 on Osteoblasts
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Guy Eelen, Els Vanoirbeek, Lieve Verlinden, Rik Gijsbers, Ine Beullens, Mark Van Camp, Ji-Hye Paik, Ronald DePinho, Roger Bouillon, Annemieke Verstuyf
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109) Adenosine A2b Receptors Induce Osteoblastogenesis Whereas A1 Receptors Induce Adipogenesis
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Borzo Gharibi, Jack Ham, Bronwen Evans
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110) Different concentrations of sodium selenite affect IGF-I and IGF-IR expression in mouse osteoblasts and regulate cells proliferation in vitro
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Gaixian Ren, Miro Ferreri, Zhi Wang, Yong Su, Bo Han
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111) Bone Morphogenetic Protein-2 - Adsorption and Release Behaviour on Clinically Relevant Materials
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Patrick Hänseler, Martin Ehrbar, Ui-Won Jung, Ronald Jung, Christoph Hämmerle, Franz Weber
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112) Post-transcriptional gene silencing using siRNA delivered from Star Nanostructured Polymer
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Joanna Hong, Eric Hsu, Abiraman Srinivasan, Cho Hong, Hyun jong Paik, Krzysztof Matyjaszewski, Jeffrey Hollinger
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113) Composite calcium phosphate chitosan coating on the basis of nanostructured hydroxyapatite coating for medical applications
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Elena Zelichenco, Valery Guzeev, Anatoly Karlov, Aleksey Shashkin, Yana Kamenchuk
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114) The role of calcium-phosphate crystals in the phosphate-dependent activation of osteoblasts
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Solmaz Khoshniat, Marion Julien, Laurent Beck, Annabelle Bourgine, Marc Petit, Thierry Rouillon, Martial Masson, Maïthé Gatius, Pierre Weiss, Jérôme Guicheux
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115) Nonlinear mechanical response of adherent cells measured by magnetic bead microrheology
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Philip Kollmannsberger, Claudia Mierke, Ben Fabry
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116) Proliferative and Osteogenic Differentiation Potentials of Human Fetal Bone Cells
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Nathalie Krattinger, Lee-Ann Applegate, Dominique Pioletti, Joseph Caverzasio
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117) REGULATION OF CYSTATHIONINE BETA SYNTHASE BY 1α,25-DIHYDROXYVITAMIN D3
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Carsten Kriebitzsch, Lieve Verlinden, Guy Eelen, Kathleen Marchal, Bart DeMoor, Ine Beullens, Mark Van Camp, Roger Bouillon, Annemieke Verstuyf
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118) Trapidil abolishes the increase in bone formation induced by ovariectomy in rats
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Hashe Kumar, Tim Chambers, Jade Chow
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119) Molecular and functional characterization of group VI calcium-independent phospholipases in osteoblast-like MC3T3-E1 cells
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Hans Leis, Werner Windischhofer
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120) MODELLING BONE HEALING DEFICIENCIES IN NF1 DEFICIENT MICE
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Jad El-Hoss, Aaron Schindeler, David Little
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121) MUSCLE PROGENITORS MAKE A MAJOR CONTRIBUTION TO OPEN FRACTURE REPAIR
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Renjing Liu, Lauren Peacock, Kathy Mikulec, Alyson Morse, Aaron Schindeler, David Little
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122) Over-expression of Specific VEGF Isoforms Differentially Enhances and Patterns Bone Formation by Modulating Angiogenesis and Osteoblast Precursors
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Christa Maes, Sonia Bartunkova, Katharina Haigh, Sophie Torrekens, Riet Van Looveren, Anna Chan, Andras Nagy, Jody Haigh, Geert Carmeliet
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123) Sox2 Is Required For The Self-renewal Of The Osteoblast Lineage
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Alka Mansukhani, Upal Basu Roy, Silvia Nicolis, Claudio Basilico
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124) Analysis of osteoblast transcriptome in osteoporosis
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Zoran Trošt, Rihard Trebse, Radko Komadina, Janja Marc
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125) Autocrine Fibroblast Growth Factor 18 mediates dexamethasone-induced osteogenic differentiation of murine mesenchymal stem cells
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Zahia Hamidouche, Olivia Fromigué, Ulrike Nuber, Pascal Vaudin, Jean-Christophe Pages, Regina Ebert, Franz Jakob, Hichem Miraoui, Pierre Marie
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126) Mesenchymal cell fraction and differentiation potential in trabecular bone of post-menopausal women
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Emanuela Mrak, Veroniquè Frattini, Isabella Villa, GianLuigi Moro, Gianfranco Fraschini, Francesca Guidobono, Alessandro Rubinacci
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127) Extracellular nucleotides regulate the expression and activity of ecto-nucleotidases by osteoblasts
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Isabel Orriss, Timothy Arnett
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128) Vertical bone formation on the CaP implant surface
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Victor Palarie, Mohamad Zahalka
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129) Identification and characterization of 2 missense mutations in the LRP4 gene causing increased bone mineral density
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Elke Piters, Olivier Leupin, Eveline Boudin, Fenna De Freitas, Manuel Bueno, Feliciano Ramos, Peter Itin, Michaela Kneissel, Wim Van Hul
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130) Relationship of uncarboxylated osteocalcin concentrations and ucOC/cOC index with the glycemic status in type 2 diabetes mellitus
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Jose Rafael Villafan Bernal, Jose Francisco Muñoz Valle, Mara Anais Llamas Covarrubias, Sergio Sanchez
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131) HIV treatments and the skeleton: Do NRTIs directly effect bone cells?
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Adam Taylor, Michael Rogers
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132) Formation of bony structures by cultured long bone osteoblasts: potent inhibition by parathyroid hormone
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Sarah Taylor, Isabel Orriss, Michelle Key, Jessal Patel, Timothy Arnett
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133) Inhibition of Osterix Expression and Osteoblast Differentiation by Wnt3a in MC3T3-E1 Cells
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Cyril Thouverey, Joseph Caverzasio
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134) Identification of Kaempferol-Regulated Proteins in Rat Calvarial Osteoblasts during Mineralization by Proteomics
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Ritu Trivedi, Avinash Kumar, Anand Singh, Abnish Gautam, Bendangla Changkija, Divya Singh, Mahendra Singh, Naibedya Chattopadhyay
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135) 17β-estradiol positively modulates GH signaling in human osteoblast-like cells
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Isabella Villa, Simona Bolamperti, Emanuela Mrak, GianLuigi Moro, Gianfranco Fraschini, Francesca Guidobono, Alessandro Rubinacci
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136) Influence of Different Bisphosphonates on Keratinocytes, HUVEC, Fibroblasts and Osteoblasts in-vitro
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Christian Walter, Thomas Ziebart, Andreas Pabst, Bilal Al-Nawas
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137) Effects of cyclic diarylheptanoids on osteoblastic differentiation and bone formation in vitro and in vivo
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Je Tae Woo, Takayuki Yonezawa, Masato Ota, Hiroyuki Akazawa, Takeda Ayano, Ji Won Lee, Masahiko Inagaki, Katsuya Kato, Byung Yoon Cha, Toshihiro Akihisa, Kazuo Nagai
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138) Spleen tyrosine kinase (Syk) suppressively regulates the osteoblastic differentiation through p44/42MAPK and PKC
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Kiyoshi Yoshida, Chikahisa Higuchi, Akio Nakura, Hideki Yoshikawa
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139) Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction
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Elazar Zelzer, Einat Blitz
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140) Urocortin prevents bone resorption by inhibiting a constitutively active transient receptor potential-like cation channel
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Charlotte Combs, Anthony Albert, Timothy Chambers, Kevin Lawrence
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141) Expression of a store-operated conductance and mRNA for canonical transient receptor potential and Orai in murine osteoclasts
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Brenda Lau, Anthony Albert, Timothy Chambers, Kevin Lawrence
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142) Calcitonin and alendronate activate Ca2+-permeable cation conductances with distinct transient receptor potential properties in murine osteoclasts
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Anthony Albert, Timothy Chambers, Kevin Lawrence
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143) GM-CSF released by osteoblasts in response to TNFalpha inhibits osteoclastogenesis in vitro
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Elvis Atanga, Silvia Dolder, Willy Hofstetter
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144) Risedronate Reduces Intracortical Porosity in Postmenopausal Women with Osteoporosis as Measured by a New 3D Micro-CT Method
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Babul Borah, Tom Dufresne, Joe Nurre, Paula Chmielewski, Roger Phipps, Leigh Mccullough, Mary Bouxsein, Roger Zebaze, Ego Seeman
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145) New Experimental Therapeutic Approach by siRNA for Autosomal Dominant Osteopetrosis (ADO)
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Andrea Del Fattore, Marta Capannolo, Nadia Rucci, Anna Teti
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146) The Corning Osteo Assay Surface for Drug Discovery. A. Fawad Faruqi, and James Beltzer
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Fawad Faruqi, James Beltzer
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147) IL-3 inhibits human osteoclast differentiation and bone resorption
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Navita Gupta, Amruta Barhanpurkar, Geetanjali Tomar, Rupesh Srivastava, Satish Pote, Gyan Mishra, Mohan Wani
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148) Conditioned medium collected from mature osteoclasts augments bone formation, while activating cartilage degradation
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Kim Henriksen, Kim Andreassen, Anita Neutzsky-Wulff, Catherine Crüger-Hansen, Suzi Høgh-Madsen, Morten Karsdal, Anne-Christine Bay-Jensen
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149) Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis
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Marc Baud'huin, Romain Renault, Céline Charrier, Anne Riet, Régis Brion, Anne Moreau, Francois Gouin, Laurence Duplomb, Dominique Heymann
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150) Autophagy and Paget's disease of bone
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Lynne Hocking, Eman Azzam, John Greenhorn, Miep Helfrich, Fraser Coxon
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151) Hypoxia-Inducible Factor (HIF) regulates Osteoclast-Mediated Bone Resorption via Angiopoietin-like 4 (ANGPTL4)
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Helen Knowles, Anne-Marie Cleton-Jansen, Eberhard Korsching, Nick Athanasou
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152) BISPHOSPHONATES AFFECT HUMAN OSTEOCLAST DEVELOPMENT IN VITRO
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Guillaume Mabilleau, Aaron Kwaasi, Afsie Sabokbar, Maria Tsoumpra, Frank Ebetino, Robert Russell
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153) Isolation and characterization of osteoclast precursors in vivo
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Toshihide Mizoguchi, Akinori Muto, Atsushi Arai, Yasuhiro Kobayashi, Nobuyuki Udagawa, Naoyuki Takahashi
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154) The N-terminal domain of the bone protein PRoline/arginine-rich End Leucine-rich repeat Protein (PRELP) impairs osteoclast formation by a new mechanism inhibiting NF-kappaB signaling
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Nadia Rucci, Anna Rufo, Marina Alamanou, Mattia Capulli, Andrea Del Fattore, Emma Åhrman, Daria Capece, Valeria Iansante, Francesca Zazzeroni, Edoardo Alesse, Dick HeinegÅrd, Anna Teti
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155) Hormone-stimulated Modulation of Endocytotic Trafficking in Osteoclasts
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Gudrun Stenbeck
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156) Identification of Growth Factors Involved in Non-canonical (MCSF Independent) Pathways of Human Osteoclast Formation
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Richard Taylor, Francesca Hemingway, Helen Knowles, Nick Athanasou
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157) Ewing's Sarcoma Cells Promote Osteoclast Formation
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Richard Taylor, Francesca Hemingway, Helen Knowles, Nick Athanasou
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158) Osteoclast Formation and Activity on Corning Osteoclast Osteo Assay Surfaces
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Jaishree Trikha, Cynthia Alander, Carol Pilbeam, Lawrence Raisz
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159) Regulation of semaphorin 3 family members and their receptors by 1α,25-dihydroxyvitamin D3
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Lieve Verlinden, Carsten Kriebitzsch, Guy Eelen, Ine Beullens, Mark Van Camp, Biauw Keng Tan, Bart De Moor, Kathleen Marchal, Roger Bouillon, Annemieke Verstuyf
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160) Skeletal status assessed by quantitative ultrasound in children with bronchial asthma
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Piotr Adamczyk, Wojciech Pluskiewicz, Zenon Halaba, Marek Nowakowski, Anna Madaj, Bogna Drozdzowska
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161) A win for bisphosphonates? Comparison between local bisphosphonate release and hydroxyapatite coating for screw fixation in rats
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Fredrik Agholme, Therese Andersson, Pentti Tengvall, Per Aspenberg
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162) Reduced serum serotonin impairs metaphyseal repair in rats
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Fredrik Agholme, Per Aspenberg
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163) Absence of bone remodeling compartment canopies correlates with deficient bone formation in post-menopausal women
Pages S67-S68
Thomas Andersen, Ellen Hauge, Jens Bollerslev, Jean-Marie Delaisse
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164) Neuropeptide Y is Critical to the Central Effects of the Endogenous Opioid System on Bone
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Paul Baldock, Frank Driessler, Iris Wong, Brigitte Kieffer, Christoph Schwarzer, Amanda Sainsbury, Herbert Herzog, John Eisman
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165) BONE MINERAL DENSITY AND LIVER DISORDERS
Pages S68-S69
Antonio Bazarra-Fernandez
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166) Bovine Lactoferrin improves bone status of ovariectomized mice via immune function modulation
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Anne Blais, Arnaud Malet, Takashi Mikogami, Daniel Tomé
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167) Mice lacking periostin are resistant to cortical bone loss induced by hind limb suspension
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Nicolas Bonnet, Laurence Vico, Serge Ferrari
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168) Change of properties of mononuclear leukocytes at patients with an osteogenesis imperfecta after operative treatment with using nanosized hydroxylapatite coatings
Pages S69-S70
Tatjana Saprina, Igor Khlusov, Alexandra Borodulina
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169) On the emergence of the spatio-temporal structure of Bone Multicellular Units
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Pascal Buenzli, Peter Pivonka, Bruce Gardiner, David Smith
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170) Relative uptake of risedronate in trabecular and cortical bone
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Frank Ebetino, Jillian Cornish, Roger Phipps, Bradley Keck, Ian Reid, Karen Callon
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171) Receptor activator of NF-kB (RANK) expression associates with bone metastasis in breast carcinomas.
Pages S70-S71
Daniele Santini, Bruno Vincenzi, Laura Gaeta, Antonio Russo, Cinzia Ortega, Camillo Porta, Nicla La Verde, Cinzia Caroti, Raffaele Addeo, Andrea Onetti Muda, Giuseppe Tonini
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172) Autocrine/paracrine action of Vitamin D on FGF23 expression in cultured rat osteoblasts
Page S71
Wen-jing Tang, Li-fang Wang, Xiao-ya Xu, Yi Zhou, Wei-fang Jin, Hong-fu Wang, Jianjun Gao
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173) The effect of cobalt and chromium ions at clinically relevant concentrations on human osteoblast and osteoclast physiology in vitro: implications for skeletal health
Page S71
Rebecca Andrews, Jeremy Wilkinson, Alison Gartland
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174) Developing injectable bone substitutes: In vitro findings and preclinical studies
Pages S71-S72
Hermann Agis, Dieter Busenlechner, Reinhard Gruber, Georg Watzek
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175) Vascular Calcification - The Role of BGP in Chondrogenic-like Differentiation of Vascular Smooth Muscle Cells
Page S72
Anna Idelevich, Efrat Monsonego Ornan
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176) Anemia and the risk of non-vertebral fractures
Page S72
Lone Jørgensen, Tove Skjelbakken, Maja-Lisa Løchen, Luai Ahmed, Åshild Bjørnerem, Ragnar Joakimsen, Bjarne Jacobsen
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177) Treatment of patients with changed bone metabolism under bisphosphonate medication - outcome of the Chemnitz long-term study
Page S73
Wigbert Linek, Karli Döring
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178) Analysis of bone mineral density and body composition at different parts and ages in chinese men
Page S73
Yukun Li, Baoxin Li, Yan Wang
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179) Analysis of bone mineral density and body composition at different parts and ages in Chinese women
Pages S73-S74
Baoxin Li, Yan Wang, Yi Huang, Yukun Li
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180) Influence of high altitude pasture on bone metabolism in goats and sheep
Page S74
Annette Liesegang, Carola Kaulfers, Kerstin Lauff, Samuel Schmid, Michael Kreuzer, Marcel Wanner, Florian Leiber
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181) EFFECTS OF BIOGENIC HYDROXYAPATITE IMPLANTS ON GROWTH AND FORMATION OF MANDIBLE IN RATS
Page S74
Vladyslav Luzin, Dmitry Astrakhantsev, Marina Solyanaya, Vitaly Morozov
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182) Osteoporotic Features in an Experimental Rat Model Caused by Liver Cirrhosis
Pages S74-S75
Xing Ma, Xiangdong Ma, Shengchun Wang, Jun Wang, Xiaoming Wu, Yongwu Hu, Mingyi Liu
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183) The differentiation and calcification of vascular smooth muscle cells is associated with an osteocyte phenotype
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Dongxing Zhu, Neil Mackenzie, Colin Farquharson, Vicky MacRae
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184) Ovariectomy-Induced Bone Resorption in the Nonhuman Primate Macaca fascicularis
Pages S75-S76
William Manton, Michael Inskip, Colin Webber
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185) Glutamatergic signals in human arthritis: A link between mechanical, nociceptive and pathological processes
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Deborah Mason, Karen Brakspear, Christopher Wilson, Rhys Williams, Rahul Kotwal
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186) Increased production of DKK-1 in fibrotic cells and osteoblasts in bone from Paget's disease
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Helen McCarthy, D. Mangham, Michael Davie, Michael Marshall
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187) HOMOZYGOUS DELETION OF DICKKOPF-1 RESULTS IN A HIGH BONE MASS PHENOTYPE
Pages S76-S77
Michelle McDonald, Alyson Morse, Paul Baldock, Lauren Peacock, Poh-Lynn Khoo, Patrick Tam, David Little
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188) The differential effects of hypoxia on the osteo-chondrogenic potential of human adipose-derived stem cells
Page S77
Christophe Merceron, Claire Vinatier, Sophie Portron, Martial Masson, Jérôme Amiaud, Lydie Guigand, Yan Chérel, Pierre Weiss, Jérôme Guicheux
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189) Chondrogenic potential human adipose-derived stem cells after in vivo transplantation with a cellulose hydrogel
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Christophe Merceron, Martial Masson, Sophie Portron, Julie Lesoeur, Virginie Grybek, Borhane Hakim Fellah, Olivier Gauthier, Pierre Weiss, Jérôme Guicheux, Claire Vinatier
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190) Effects of oxygen tension on the chondrogenic potential of differentially cultured human adipose-derived stem cells
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Christophe Merceron, Martial Masson, Sophie Portron, Julie Lesoeur, Virginie Grybek, Borhane Hakim Fellah, Olivier Gauthier, Pierre Weiss, Jérôme Guicheux, Claire Vinatier
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191) Loss of bone mineralization by the simultaneous ablation of PHOSPHO1 and alkaline phosphatase function
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Jose Luis Millan, Manisha Yadav, Ana Simao, Sonoko Narisawa, Carmen Huesa, Marc McKee, Colin Farquharson
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192) SOCS2 Regulates Growth by Inhibiting GH Signalling in Chondrocytes
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Chloe Pass, Vicky MacRae, Syed Ahmed, Colin Farquharson
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193) Prevalence of neutralising antibodies to osteoprotegerin in autoimmune disease and severe osteoporosis
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Philip Riches, Catherine Determann, Rob van't Hof, Stuart Ralston
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194) MECHANISMS INDUCING LOW BONE DENSITY IN DUCHENNE MUSCULAR DYSTROPHY
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Anna Rufo, Andrea Del Fattore, Maria Bianchi, Enrico Bertini, Antonio Musarò, Serge Ferrari, Dominique Pierroz, Mattia Capulli, Nadia Rucci, Lucia Morandi, Fabrizio De Benedetti, Anna Teti
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195) Effects of a sulphated exopolysaccharide produced by Alteromonas infernus on bone cells
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Carmen Ruiz Velasco, Sylvia Colliec-Jouault, Dominique Heymann, Marc Padrines
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196) Lean Body Mass, Not Total Body Size, is a Stronger Determinant of Total Body Bone Mass in Boys
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Tom Sanchez, Jingmei Wang, Chad Dudzek, George Ekker, Kathy Dudzek
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197) Osteogenesis with BMP-2 variant L51P in a critical size defect model in rats
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Hans-Jörg Sebald, Mark Siegrist, Frank Klenke, Willy Hofstetter, Walter Sebald
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198) Interleukin-1-beta disrupts normal chondrogenesis and growth plate development
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Stav Simsa-Maziel, Efrat Monsonego Ornan
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199) Oleoyl Serine, an Endogenous Regulator of Skeletal Mass
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Reem Smoum, Arik Bar, Bo Tan, Garry Milman, Malka Attar-Namdar, Orr Ofek, Jordyn Stuart, Alon Bajayo, Yossef Tam, Vardit Kram, David O'Dell, Michael Walker, Heather Bradshaw, Raphael Mechoulam, Itai Bab
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200) Effects of oxygen tension on the hypertrophic terminal differentiation of chondrogenic cells
Pages S81-S82
Portron Sophie, Christophe Merceron, Masson Martial, Maïthé Gatius, Pierre Weiss, Olivier Gauthier, Jerome Guicheux, Claire Vinatier
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201) EFFECTS OF ELECTROMAGNETIC FIELD AND CHLOROBENZENES TREATMENT ON BONE AND CONNECTIVE TISSUE IN RATS
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Zsuzsanna Valkusz, Mariann Radács, Márta Gálfi, Janos Julesz
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202) Osteonecrosis of jaw and pathological fracture in patients with bisphosphonates treatment
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Vaclav Vyskocil, Luboš Hauer, Daniel Hrušák, Petr Mukensnabl
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203) Quantification of the Order in the Spatial Arrangement of Secondary Osteons in Equine and Canine Long Bones
Page S83
Richard Weinkamer, John Dunlop, Sharon Papo, Carolin Lukas, Ron Shahar
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204) IBMS Davos Workshops: Author Index
Pages S84-S87
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205) IBMS Davos Workshops: Keywords Index
Pages S88-S89
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