[Ortho] Aspirin Can Be Used as Prophylaxis for Prevention of Venous Thromboembolism After Revision Hip and Knee Arthroplasty

Александр Ларионов alarionov2011 на gmail.com
Пт Ноя 4 05:33:30 YEKT 2016


п░ я│ п╨я│п╟я─п╣п╩я┌п╬ п╦ п©я─.?

1 п╫п╬я▐п╠. 2016 пЁ. 8:53 п©п╬п╩я▄п╥п╬п╡п╟я┌п╣п╩я▄ "Alexander Chelnokov" <
orthoforum на weborto.net> п╫п╟п©п╦я│п╟п╩:

> п░я│п©п╦я─п╦п╫ п╬п©я▐я┌я▄ п╩я┐я┤я┬п╣ п╡п╟я─я└п╟я─п╦п╫п╟ п╢п╩я▐ п©я─п╬я└п╦п╩п╟п╨я┌п╦п╨п╦ я┌я─п╬п╪п╠п╬я█п╪п╠п╬п╩п╦я┤п╣я│п╨п╦я┘
> п╬я│п╩п╬п╤п╫п╣п╫п╦п╧... п²п╣ п©п╬я─п╟ п╩п╦ п©п╣я─п╣я│п╪п╟я┌я─п╦п╡п╟я┌я▄ п╨п╩п╦п╫п╦я┤п╣я│п╨п╦п╣ я─п╣п╨п╬п╪п╣п╫п╢п╟я├п╦п╦?
>
> J Arthroplasty. 2016 Oct;31(10):2237-40. doi:
> 10.1016/j.arth.2016.03.031. Epub 2016 Mar 30.
>
> Aspirin Can Be Used as Prophylaxis for Prevention of Venous
> Thromboembolism After Revision Hip and Knee Arthroplasty.
>
> Deirmengian GK1, Heller S1, Smith EB1, Maltenfort M1, Chen AF1, Parvizi J1.
>
> Author information
>
> 1Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, PA.
>
> Abstract
>
> BACKGROUND:
>
> The optimal prophylaxis for prevention of venous thromboembolic events
> (VTEs) after revision total joint arthroplasty (TJA) remains unknown.
> The objective of this study was to evaluate whether aspirin, known to be
> effective for prevention of VTEs after primary arthroplasty, is also
> effective after revision TJA.
>
>
>
> METHODS:
>
> We studied 2997 consecutive patients who underwent revision TJA between
> 2005 and 2013 and were treated with intermittent pneumatic compression
> devices and either aspirin (534 patients) or warfarin (2463 patients)
> for VTE prophylaxis. Pertinent data including the incidence of
> symptomatic VTEs, bleeding events, infection, and mortality were
> retrieved from our prospectively collected database.
>
>
>
> RESULTS:
>
> The incidence of symptomatic VTEs was significantly higher in the
> warfarin group at 1.75% (43 of 2463) compared with 0.56% (3 of 534) in
> the aspirin group (odds ratio: 3.2; 95% CI: 1.03-16.3; P = .03). There
> was a higher rate of bleeding events with administration of warfarin
> (1.5%) compared with aspirin (0.4%; P = .02; odds ratio: 4.1; 95% CI:
> 1.2-34.0). The rate of surgical site infection was similar between the
> aspirin group and the warfarin group (1.61% and 1.70%, respectively).
>
>
>
> CONCLUSION:
>
> Administration of aspirin as prophylaxis against VTEs after revision
> arthroplasty may be a viable option as it appears to be more effective
> than warfarin in prevention of symptomatic VTEs and is associated with a
> lower rate of complications.
>
>
>
> PMID: 27118182 DOI: 10.1016/j.arth.2016.03.031
>
> https://www.ncbi.nlm.nih.gov/pubmed/27118182
>
> Alexander Chelnokov
>
>
>
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